Articles: nausea.
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Randomized Controlled Trial Comparative Study
Ondansetron versus promethazine to treat acute undifferentiated nausea in the emergency department: a randomized, double-blind, noninferiority trial.
The authors sought to compare ondansetron and promethazine among emergency department (ED) patients with undifferentiated nausea. The hypothesis was that ondansetron was not inferior to promethazine and that rates of adverse effects were similar. ⋯ Promethazine and ondansetron have similar efficacy in reducing nausea among ED patients. Change in anxiety was similar, but promethazine was associated with greater sedation.
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Palliative medicine · Mar 2008
Letter Randomized Controlled TrialDoes acupressure help reduce nausea and vomiting in palliative care patients? Pilot study.
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J Laparoendosc Adv Surg Tech A · Feb 2008
Randomized Controlled Trial Comparative StudyDoes preoperative hydration affect postoperative nausea and vomiting? A randomized, controlled trial.
It has been suggested that relative hypovolemia due to overnight fasting may result in postoperative nausea and vomiting (PONV). The aim of this study was to investigate the effect of preoperative and intraoperative hydration (the necessary amount of fluid preoperatively to cover the fluid deficit) on PONV. ⋯ PONV was reduced when the fluid deficit was replaced preoperatively.
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Randomized Controlled Trial Comparative Study
Acupressure for chemotherapy-associated nausea and vomiting in children.
The objective of this study was to determine the feasibility and effectiveness of acupressure therapy in preventing chemotherapy-associated nausea in children. A prospective, randomized, crossover trial was conducted among pediatric oncology patients at Brenner Children's Hospital (Winston-Salem, NC). Patients were randomized to one of two treatment sequences involving acupressure wrist bands and placebo bands, separated by a standard care treatment with no bands. ⋯ There was no significant difference in nausea or vomiting between the three groups; there were no significant side effects from acupressure or placebo bands. Pediatric oncology patients have moderate expectations about the effectiveness of acupressure in preventing nausea and vomiting. Acupressure is feasible and well tolerated but was not more effective than placebo in this sample of patients who were also treated with standard antiemetic therapies.
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Eur J Cancer Care (Engl) · Nov 2007
Randomized Controlled TrialEffects of an integrated yoga programme on chemotherapy-induced nausea and emesis in breast cancer patients.
This study examined the effect of an integrated yoga programme on chemotherapy-related nausea and emesis in early operable breast cancer outpatients. Sixty-two subjects were randomly allocated to receive yoga (n = 28) or supportive therapy intervention (n = 34) during the course of their chemotherapy. Both groups had similar socio-demographic and medical characteristics. ⋯ Following yoga, there was a significant decrease in post-chemotherapy-induced nausea frequency (P = 0.01) and nausea intensity (P = 0.01), and intensity of anticipatory nausea (P = 0.01) and anticipatory vomiting (P = 0.05) as compared with the control group. There was a significant positive correlation between MANE scores and anxiety, depression and distressful symptoms. In conclusion, the results suggest a possible use for stress reduction interventions such as yoga in complementing conventional antiemetics to manage chemotherapy-related nausea and emesis.