Articles: nausea.
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Outpatient surgery has become increasingly popular. Technical advances in both surgery and anesthesia have made the practice of ambulatory surgery safe and attractive. ⋯ The valid patient complaint of postoperative nausea and vomiting has been shown to significantly delay discharge from the recovery area after ambulatory surgery. This article reviews the numerous factors that have been identified as fostering the postoperative complication of nausea and vomiting.
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At the beginning of the 80's the Italian Group for Clinical Research (G. O. I. ⋯ Today, the interest of the Group is concentrated in studying the optimal antiemetic prophylaxis for delayed emesis induced by moderately emetogenic chemotherapy. The rules always followed by the Italian Group for Antiemetic Research are: --complete independence of judgement on the efficacy and the tolerability of antiemetic drugs from the pharmaceutical companies; --priority of ethical problems in designing clinical trials; --strict adherence to the methodological problems of antiemetic research and--complete autonomy concerning the study planned, the data computerization and the data elaboration. In the last twelve years approximately 70 Italian centres have enrolled their patients into the studies of the Italian Group for Antiemetic Research.