Articles: brain-injuries.
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Zh Nevrol Psikhiatr · Jan 1995
[The characteristics of a psycho-autonomic syndrome in the sequelae of closed craniocerebral trauma].
Some clinical characteristics of posttraumatic psychovegetative syndrome, associated with nonspecific brain systems disfunctions were defined more precisely on the basis of the clinical estimation of vegetative, psychological as well as polygraphic indexes of sleep-awakening cycle in 205 patients with the consequences of closed craniocerebral trauma (CCT). It was mentioned that the characteristics features of such psychovegetative syndrome turned out to be: in vegetative sphere the clear parasympathetic displacement of main cardiovascular characteristics. ⋯ The discussion of results obtained was performed. The psychovegetative pattern revealed was worthwhile in different diagnosis of CCT with diseases of other etiology as well as both elaboration and improvement of rehabilitation system of patients with CCT consiquences.
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Journal of neurotrauma · Dec 1994
Combined fluid percussion brain injury and entorhinal cortical lesion: a model for assessing the interaction between neuroexcitation and deafferentation.
Laboratory studies suggest that excessive neuroexcitation and deafferentation contribute to long-term morbidity following human head injury. Because no current animal model of traumatic brain injury (TBI) has been shown to combine excessive neuroexcitation and significant levels of deafferentation, we developed a rat model combining the neuroexcitation of fluid percussion TBI with subsequent entorhinal cortical (EC) deafferentation. In this paradigm, moderate fluid percussion TBI was induced in each rat, followed 24 h later by bilateral EC lesion (BEC). ⋯ Specifically, the laminar pattern of presynaptic rearrangement induced by BEC lesion did not occur after TBEC injury. The present results show that axonal injury and its attendant deafferentation, when coupled with traumatically induced neuroexcitation, produce an enhancement of the morbidity associated with TBI. Moreover, they indicate that this model can effectively be used to study the interaction between neuroexcitation and synaptic plasticity.