Initial liberal fluid resuscitation strategies in trauma patients may be associated with higher mortality.
There is limited evidence supporting superiority between plain or hyperbaric spinal bupivacaine for spinal cesarean section.
Fentanyl-only epidural infusion shows no benefit over fentanyl/bupiv in respect to duration of labor, motor block, delivery, analgesia, or outcomes.
Opioid sparing is a feasible pragmatic endpoint for pediatric pain analgesic trials.
Local infiltration with either 50mL 0.5% or 125mL 0.2% ropivacaine did not improve post-operative pain after elective caesarean section.
It is likely that there is an interaction between tramadol and ondansetron that decreases the early-postoperative analgesic efficacy of tramadol.
Higher dosing, waiting longer or combining with an opioid improve mivacurium intubating conditions, particularly in older patients.
Either proximal or distal sciatic nerve block reduces pain in the first 6 hours after total knee arthroplasty. Distal (popliteal) may be superior.
Intraoperative ketamine and magnesium improves post-operative analgesia after scoliosis surgery when compared to ketamine alone.
Dexamethasone 8 mg has equal effect in prolonging single-shot supraclavicular block whether given perineurial or intravenously.
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