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Also worth considering, is the impact that CPR and external compressions may have on undermining the effective protection of PPE, given that CPR is a uniquely dynamic and physical activity compared to most medical procedures.
Using simulation studies, Hwang et al. have already brought into question the effectiveness of N95 masks during CPR:
N95 respirator masks may not provide adequate protection during chest compressions, even when resuscitators have passed quantitative fit testing.
Couper K, Taylor-Phillips S, Grove A et al. COVID-19 in cardiac arrest and infection risk to rescuers: a systematic review. Resuscitation. 2020 Jun 1; 151: 59-66.
  Daniel Jolley
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Some of the assertions in this review are challengable, and based upon sources with lesser certainty than suggested. For example:
"COVID-19 is predominantly caused by contact or droplet transmission..." - Cook
Yet the reference for this is a Public Health England statement describing this as an 'assumption' without evidence. In contrast there is now considerable debate as to the significance of airborne COVID-19 transmission.
"The transmission of COVID-19 is thought to occur mainly through respiratory droplets generated by coughing and sneezing, and through contact with contaminated surfaces. The predominant modes of transmission are assumed to be droplet and contact." – Public Health England
Because PPE recommendations are based upon this assumption, caution is still required.
Cook TM. Personal protective equipment during the COVID-19 pandemic - a narrative review. Anaesthesia. 2020 Jul 1; 75 (7): 920-927.
  Daniel Jolley
pearl
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N95 respirator masks may not provide adequate protection during chest compressions, even when resuscitators have passed quantitative fit testing.
Hwang SY, Yoon H, Yoon A et al. N95 filtering facepiece respirators do not reliably afford respiratory protection during chest compression: A simulation study. Am J Emerg Med. 2020 Jan 1; 38 (1): 12-17.
  Daniel Jolley
pearl
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Awareness of the high-risk steps during PPE donning and doffing offers disproportionate safety benefits.
Muñoz-Leyva F Niazi AU. Common breaches in biosafety during donning and doffing of protective personal equipment used in the care of COVID-19 patients. Can J Anaesth. 2020 Jul 1; 67 (7): 900-901.
  Daniel Jolley
pearl
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Peri-operative intravenous crystalloid probably reduces the risk of postoperative nausea and vomiting.
Jewer JK, Wong MJ, Bird SJ et al. Supplemental peri-operative intravenous crystalloids for postoperative nausea and vomiting: an abridged Cochrane systematic review. Anaesthesia. 2020 Feb 1; 75 (2): 254-265.
  Daniel Jolley
pearl
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Sugammadex anaphylaxis risk is greater than for neostigmine.
Orihara M, Takazawa T, Horiuchi T et al. Comparison of incidence of anaphylaxis between sugammadex and neostigmine: a retrospective multicentre observational study. Br J Anaesth. 2020 Feb 1; 124 (2): 154-163.
  Daniel Jolley
pearl
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Intraoperative and postoperative hypotension are both associated with postoperative delirium among patients admitted to ICU.
Maheshwari K, Ahuja S, Khanna AK et al. Association Between Perioperative Hypotension and Delirium in Postoperative Critically Ill Patients: A Retrospective Cohort Analysis. Anesth. Analg. 2020 Mar 1; 130 (3): 636-643.
  Daniel Jolley
pearl
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Non-orthopaedic surgery is associated with a post-operative discontinuation of opioid use among chronic users.
Jivraj NK, Scales DC, Gomes T et al. Evaluation of opioid discontinuation after non-orthopaedic surgery among chronic opioid users: a population-based cohort study. Br J Anaesth. 2020 Mar 1; 124 (3): 281-291.
  Daniel Jolley
pearl
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Up to 50% of contagious COVID-19 patients are asymptomatic or pre-symptomatic.
Gandhi M, Yokoe DS, Havlir DV. Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19. N. Engl. J. Med. 2020 May 28; 382 (22): 2158-2160.
  Daniel Jolley
pearl
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PPE doffing carries significant risk for self-contamination. Assisted doffing likely reduces this risk.
Chughtai AA, Chen X, Macintyre CR. Risk of self-contamination during doffing of personal protective equipment. Am J Infect Control. 2018 Dec 1; 46 (12): 1329-1334.
  Daniel Jolley