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pearl
1
Non-orthopaedic surgery is associated with a post-operative discontinuation of opioid use among chronic users.
Jivraj NK, Scales DC, Gomes T et al. Evaluation of opioid discontinuation after non-orthopaedic surgery among chronic opioid users: a population-based cohort study. Br J Anaesth. 2020 Mar 1; 124 (3): 281-291.
  Daniel Jolley
pearl
1
Up to 50% of contagious COVID-19 patients are asymptomatic or pre-symptomatic.
Gandhi M, Yokoe DS, Havlir DV. Asymptomatic Transmission, the Achilles' Heel of Current Strategies to Control Covid-19. N. Engl. J. Med. 2020 May 28; 382 (22): 2158-2160.
  Daniel Jolley
pearl
1
PPE doffing carries significant risk for self-contamination. Assisted doffing likely reduces this risk.
Chughtai AA, Chen X, Macintyre CR. Risk of self-contamination during doffing of personal protective equipment. Am J Infect Control. 2018 Dec 1; 46 (12): 1329-1334.
  Daniel Jolley
pearl
1
Personal protective equipment (PPE) may significantly reduce first-pass intubation success for trainees, primarily due to the visibility impact of protective hoods.
Scott R, Pitzer M, Goldman G et al. Comparison of intubation devices in level C personal protective equipment: A cadaveric study. Am J Emerg Med. 2018 Jun 1; 36 (6): 922-925.
  Daniel Jolley
pearl
1
Transmission of SARS-CoV-2 should be conceptualised as a spectrum of risk where time exposed may be the dominant factor.
Wilson NM, Norton A, Young FP et al. Airborne transmission of severe acute respiratory syndrome coronavirus-2 to healthcare workers: a narrative review. Anaesthesia. 2020 Aug 1; 75 (8): 1086-1095.
  Daniel Jolley
pearl
1
SARS-CoV-2 viral particles can travel large distances, detected at up to 4 meters, and remaining in air up to 3 hours after aerosolisation, although with uncertain infective viability.
Bahl P, Doolan C, de C et al. Airborne or droplet precautions for health workers treating COVID-19? J. Infect. Dis. 2020 Apr 16.
  Daniel Jolley
pearl
1
The incubation time of SARS-CoV-2, the causative agent of COVID-19, is comparable to both SARS and MERS.
Jiang X, Rayner S, Luo MH. Does SARS-CoV-2 has a longer incubation period than SARS and MERS? J. Med. Virol. 2020 May 1; 92 (5): 476-478.
  Daniel Jolley
pearl
1
Remifentanil and alfentanil effectively reduce the pressor response to intubation for general anaesthesia cesarean section, without depressing neonatal Apgar scores.
White LD, Hodsdon A, An GH et al. Induction opioids for caesarean section under general anaesthesia: a systematic review and meta-analysis of randomised controlled trials. Int J Obstet Anesth. 2019 Nov 1; 40: 4-13.
  Daniel Jolley
pearl
1
Maternal obesity increases the risk of epidural failure (OR 1.8) and difficult insertion requiring multiple attempts (OR 2.2).
Uyl N, de E, Uyl-de C et al. Difficult epidural placement in obese and non-obese pregnant women - A systematic review and meta-analysis. Int J Obstet Anesth. 2019 Nov 1; 40: 52-61.
  Daniel Jolley
pearl
1
"When considering preparation for the next pandemic, it is not a matter of if it will occur, but rather a matter of when." – Kain & Fowler
Kain T Fowler R. Preparing intensive care for the next pandemic influenza. Crit Care. 2019 Oct 30; 23 (1): 337337.
  Daniel Jolley