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pearl
1
Intravenous dexamethasone at all studied doses did not prolong median nerve block.
Short A, El-Boghdadly K, Clarke H et al. Effect of intravenous dexamethasone on the anaesthetic characteristics of peripheral nerve block: a double-blind, randomised controlled, dose-response volunteer study. Br J Anaesth. 2020 Jan 1; 124 (1): 92-100.
  Daniel Jolley
pearl
1
Perioperative high inspired oxygen concentrations do not reduce surgical site infections – and may possibly increase infection incidence.
Pryor KO, Fahey TJ, Lien CA et al. Surgical site infection and the routine use of perioperative hyperoxia in a general surgical population: a randomized controlled trial. JAMA. 2004 Jan 7;291(1):79-87.
  Daniel Jolley
pearl
1
High inspired oxygen concentrations intraoperatively do not reduce surgical site infections, and may potentially have detrimental effects.
Wetterslev J, Meyhoff CS, Jørgensen LN et al. The effects of high perioperative inspiratory oxygen fraction for adult surgical patients. Cochrane Db Syst Rev. 2015 Jun 25; 2015 (6): CD008884CD008884.
  Daniel Jolley
pearl
1
No difference in post-operative atelectasis was observed after non-abdominal surgery for patients having PEEP either maintained or withdrawn before emergence.
Östberg E, Thorisson A, Enlund M et al. Positive End-expiratory Pressure and Postoperative Atelectasis: A Randomized Controlled Trial. Anesthesiology. 2019 Oct 1; 131 (4): 809-817.
  Daniel Jolley
pearl
1
In the context of optimal, individualised lung ventilation, high inspired oxygen does not reduce surgical infections compared with conventional FiO2.
Ferrando C, Aldecoa C, Unzueta C et al. Effects of oxygen on post-surgical infections during an individualised perioperative open-lung ventilatory strategy: a randomised controlled trial. Br J Anaesth. 2020 Jan 1; 124 (1): 110-120.
  Daniel Jolley
pearl
1
There is no clinically significant difference in the duration of low-dose interscalene block between perineural and intravenous dexamethasone.
McHardy PG, Singer O, Awad IT et al. Comparison of the effects of perineural or intravenous dexamethasone on low volume interscalene brachial plexus block: a randomised equivalence trial. Br J Anaesth. 2020 Jan 1; 124 (1): 84-91.
  Daniel Jolley
pearl
1
Intraoperative PEEP and recruitment manoeuvres reduce ultrasound-detected atelectasis intraoperatively but showed no post-extubation benefit after open gynaecological surgery.
Généreux V, Chassé M, Girard F et al. Effects of positive end-expiratory pressure/recruitment manoeuvres compared with zero end-expiratory pressure on atelectasis during open gynaecological surgery as assessed by ultrasonography: a randomised controlled trial. Br J Anaesth. 2020 Jan 1; 124 (1): 101-109.
  Daniel Jolley
pearl
1
A relational coordination framework can be readily applied to both simulation research and application.
Brazil V, Purdy E, Alexander C et al. Improving the relational aspects of trauma care through translational simulation. Adv Simul (Lond). 2019 Jan 1; 4: 10.
  Daniel Jolley
pearl
1
Hospitals more actively using in situ cardiac arrest drills show significantly higher survival to discharge after in-hospital cardiac arrest.
Josey K, Smith ML, Kayani AS et al. Hospitals with More-active Participation in Conducting Standardized In-situ Mock Codes have Improved Survival After In-hospital Cardiopulmonary Arrest. Resuscitation. 2018 Dec 1; 133: 47-52.
  Daniel Jolley
pearl
1
A significant proportion of women do not recall intrapartum information before labour analgesia (38%) or anaesthesia for cesarean section (72%). Verbally-provided information was best recalled.
Brinkler R, Edwards Z, Abid S et al. A survey of antenatal and peripartum provision of information on analgesia and anaesthesia. Anaesthesia. 2019 Sep 1; 74 (9): 1101-1111.
  Daniel Jolley