Anesthesia neurotoxicity may affect the developing human brain, however methodological challenges limit the conclusiveness of current evidence.
Intravenous lidocaine is efficacious and may be a suitable alternative to regional anesthesia when contraindicated or not performed.
Nerve blocks in general have a beneficial analgesic effect, regardless of whether pre- or post-incision, and are superior to intra-articular LA.
Use of the LMA ProSeal when compared with intubation for gynae-laparoscopy does not decrease post-operative pain or PONV.
Perioperative lidocaine reduces the incidence of persistent post-surgical pain after breast cancer surgery.
Non-technical skills are of equal importance to technical anaesthesia skills, but are more challenging to define, measure and acquire.
Meta-analysis suggests regional scalp block may reduce post-operative pain after craniotomy, although relies on small, low-quality studies.
30mg intraperitoneal nebulized ropivacaine significantly reduces pain after laparoscopic cholecystectomy, reducing opioid use and speeding ambulation.
Implementation of a Surgical Safety Checklist had a positive, though small, impact on the theatre safety culture in a Norwegian university hospital.
Renal impairment as indicated by low eGFR is associated with early post-operative mortality, particularly following cardiac or vascular surgery.
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