• Lancet neurology · Jul 2020

    Review

    Brain injury after cardiac arrest: from prognostication of comatose patients to rehabilitation.

    • Tobias Cronberg, David M Greer, Gisela Lilja, Véronique Moulaert, Paul Swindell, and Andrea O Rossetti.
    • Department of Clinical Sciences, Neurology, Lund University, Skane University Hospital, Lund, Sweden. Electronic address: tobias.cronberg@skane.se.
    • Lancet Neurol. 2020 Jul 1; 19 (7): 611-622.

    AbstractMore patients are surviving cardiac arrest than ever before; however, the burden now lies with estimating neurological prognoses in a large number of patients who were initially comatose, in whom the ultimate outcome is unclear. Neurologists, neurointensivists, and clinical neurophysiologists must accurately balance the concern that overly conservative prognostication could leave patients in a severely disabled state, with the possibility that inaccurately pessimistic prognostication could lead to the withdrawal of life-sustaining treatment in patients who might otherwise have a good functional outcome. Prognostic tools have improved greatly, including electrophysiological tests, neuroimaging, and chemical biomarkers. Conclusions about the prognosis should be delayed at least 72 h after arrest to allow for the clearance of sedative drugs. Cognitive impairments, emotional problems, and fatigue are common among patients who have survived cardiac arrest, and often go unrecognised despite being related to caregiver burden and a decreased participation in society. Through simple screening, these problems can be identified, and patients can be provided with adequate information and rehabilitation.Copyright © 2020 Elsevier Ltd. All rights reserved.

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