• Internal medicine · Nov 2020

    Review Case Reports

    Lupus Aortitis Successfully Treated with Moderate-dose Glucocorticoids: A Case Report and Review of the Literature.

    • Hiroyuki Akebo, Ryuichi Sada, Sho Matsushita, Hiroyasu Ishimaru, Saki Minoda, Hirofumi Miyake, Yukio Tsugihashi, and Kazuhiro Hatta.
    • Department of General Internal Medicine, Tenri Hospital, Japan.
    • Intern. Med. 2020 Nov 1; 59 (21): 2789-2795.

    AbstractLupus aortitis is a rare and potentially life-threatening disorder. Previous studies have reported the utility of high-dose systemic glucocorticoids or surgery as the treatment, although there have been no related controlled trials. We herein report a 49-year-old woman with a 35-year history of systemic lupus erythematosus who was diagnosed with aortitis. Her symptoms and laboratory and imaging abnormalities rapidly resolved upon the administration of moderate-dose glucocorticoids. We subsequently performed a literature review of similar cases to identify the appropriate treatment and discuss these cases. A study of further cases will be needed to identify the characteristics of patients who would benefit from moderate-dose glucocorticoid therapy.

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