• Medicine · Aug 2020

    Effects of spore powder of ganoderma lucidum on CaSR and apoptosis-related proteins in hippocampus tissue of epilepsy following dementia: A protocol of systematic review.

    • Li-Hong Qin, Chen Wang, Xiao-Xue Jiang, You Song, Yao Feng, Li-Wei Qin, and Shu-Ping Zhang.
    • aFirst Ward of Neurology Department bSecond Ward of Neurology Department cDepartment of Quality Control Center dDepartment of Chinese Medicine eDepartment of Physical Diagnosis, First Affiliated Hospital of Jiamusi University, Jiamusi, China.
    • Medicine (Baltimore). 2020 Aug 14; 99 (33): e21711.

    BackgroundThis study will investigate the effects of Spore Powder of Ganoderma Lucidum (SPGL) on CaSR and apoptosis-related proteins (ARP) in hippocampus tissue of epilepsy following dementia.MethodsThis study will retrieve all potential studies from both electronic databases (Cochrane Library, EMBASE, MEDLINE, CINAHL, AMED, and CNKI) and other literature sources to assess the effects of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia. We will search all literature sources from the inception to the present. All eligible case-control studies will be included in this study. Two authors will independently carry out literature selection, data collection, and study quality evaluation. Any divergence will be resolved by another author through discussion. RevMan 5.3 software will be employed for data analysis.ResultsThis study will summarize existing evidence to assess the effects of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia.ConclusionsThe findings of this study may provide helpful evidence of SPGL on CaSR and ARP in hippocampus tissue of epilepsy following dementia.Systematic Review RegistrationINPLASY202070041.

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