• Ned Tijdschr Geneeskd · Mar 2020

    [Chloroquine as a possible treatment for COVID-19].

    • Jeroen Coumou and Peter J de Vries.
    • Tergooi Ziekenhuis, afd. Interne Geneeskunde, Hilversum.
    • Ned Tijdschr Geneeskd. 2020 Mar 11; 164.

    AbstractSince the outbreak of COVID-19, chloroquine has been mentioned as a possible treatment. In vitro studies have shown anti-viral activity of chloroquine against SARS-CoV-2. Recently, the Dutch National Institute for Public Health and the Environment published treatment options for antiviral treatment for COVID-19 where chloroquine was suggested as first choice for off-label treatment, beside remdesivir en lopinavir/ritonavir. In this commentary, we provide a background and history of chloroquine, the evidence for antiviral efficacy of chloroquine and the arguments for off-label use of chloroquine in COVID-19.

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