• Postgrad Med J · Jun 2021

    Review

    Is HbA1c an ideal biomarker of well-controlled diabetes?

    • Georgia Kaiafa, Stavroula Veneti, George Polychronopoulos, Dimitrios Pilalas, Stylianos Daios, Ilias Kanellos, Triantafyllos Didangelos, Stamatina Pagoni, and Christos Savopoulos.
    • First Propedeutic Department of Internal Medicine, AHEPA University Hospital, Medical School, Aristotle University of Thessaloniki, Greece gdkaiafa@yahoo.gr.
    • Postgrad Med J. 2021 Jun 1; 97 (1148): 380383380-383.

    AbstractHbA1c is a biomarker with a central role in the diagnosis and follow-up of patients with diabetes, although not a perfect one. Common comorbidities encountered in patients with diabetes mellitus, such as renal insufficiency, high output states (iron deficiency anaemia, haemolytic anaemia, haemoglobinopathies and pregnancy) and intake of specific drugs could compromise the sensitivity and specificity of the biomarker. COVID-19 pandemic poses a pressing challenge for the diabetic population, since maintaining optimal blood glucose control is key to reduce morbidity and mortality rates. Alternative methods for diabetes management, such as fructosamine, glycosylated albumin and device-based continuous glucose monitoring, are discussed.© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.

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