• Hualiang Lin, Tao Liu, Tie Song, Lifeng Lin, Jianpeng Xiao, Jinyan Lin, Jianfeng He, Haojie Zhong, Wenbiao Hu, Aiping Deng, Zhiqiang Peng, Wenjun Ma, and Yonghui Zhang.
• Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou, China.
• PLoS Negl Trop Dis. 2016 Aug 1; 10 (8): e0004919.

BackgroundAn explosive outbreak of dengue fever occurred in Guangdong Province, China in 2014. A community-based integrated intervention was applied to control this outbreak in the capital city Guangzhou, where dengue epidemic was mainly caused by imported cases.Methodology/Principal FindingsWe used a time series generalized additive model based on meteorological factors to assess the effectiveness of this intervention. The results showed that there was significant reduction in mosquito density following the intervention, and there was a 70.47% (95% confidence interval: 66.07%, 74.88%) reduction in the reported dengue cases compared with the predicted cases after 12 days since the beginning of the intervention, we estimated that a total of 23,302 dengue cases were prevented.ConclusionsThis study suggests that an integrated dengue intervention program has significant effects to control a dengue outbreak in areas where dengue epidemic was mainly caused by imported dengue cases.

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