• Ayling Oliver G S OGS Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, Canada., Tamir Ailon, John T Street, Nicolas Dea, Greg McIntosh, Edward Abraham, W Bradly Jacobs, Alex Soroceanu, Michael G Johnson, Jerome Paquet, Parham Rasoulinejad, Phillipe Phan, Albert Yee, Sean Christie, Andrew Nataraj, R Andrew Glennie, Hamilton Hall, Neil Manson, Y Raja Rampersaud, Kenneth Thomas, and Charles G Fisher.
• Department of Surgery, Vancouver General Hospital/University of British Columbia, Vancouver, Canada.
• Neurosurgery. 2021 Jan 13; 88 (2): 420-427.

BackgroundPerioperative adverse events (AEs) lead to patient disappointment and greater costs. There is a paucity of data on how AEs affect long-term outcomes.ObjectiveTo examine perioperative AEs and their impact on outcome after lumbar spine surgery.MethodsA total of 3556 consecutive patients undergoing surgery for lumbar degenerative disorders enrolled in the Canadian Spine Outcomes and Research Network were analyzed. AEs were defined using the validated Spine AdVerse Events Severity system. Outcomes at 3, 12, and 24 mo postoperatively included the Owestry Disability Index (ODI), 12-Item Short-Form Health Survey (SF-12) Physical (PCS) and Mental (MCS) Component Summary scales, visual analog scale (VAS) leg and back, EuroQol-5D (EQ5D), and satisfaction.ResultsAEs occurred in 767 (21.6%) patients, and 85 (2.4%) patients suffered major AEs. Patients with major AEs had worse ODI scores and did not reach minimum clinically important differences at 2 yr (no AE: 25.7 ± 19.2, major: 36.4 ± 19.1, P < .001). Major AEs were associated with worse ODI scores on multivariable linear regression (P = .011). PCS scores were lower after major AEs (43.8 ± 9.5, vs 37.7 ± 20.3, P = .002). On VAS leg and back and EQ5D, the 2-yr outcomes were significantly different between the major and no AE groups (<0.01), but these differences were small (VAS leg: 3.4 ± 3.0 vs 4.0 ± 3.3; VAS back: 3.5 ± 2.7 vs 4.5 ± 2.6; EQ5D: 0.75 ± 0.2 vs 0.64 ± 0.2). SF12 MCS scores were not different. Rates of satisfaction were lower after major AEs (no AE: 84.6%, major: 72.3%, P < .05).ConclusionMajor AEs after lumbar spine surgery lead to worse functional outcomes and lower satisfaction. This highlights the need to implement strategies aimed at reducing AEs.Copyright © 2020 by the Congress of Neurological Surgeons.

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