• J Clin Anesth · Jun 2012

    Case Reports

    Perioperative retinoic acid syndrome in a patient with acute promyelocytic leukemia.

    • Nikolay A Usoltsev and M Saeed Dhamee.
    • Department of Anesthesiology, Medical College of Wisconsin, Milwaukee, WI 53226, USA. usnickolay@gmail.com
    • J Clin Anesth. 2012 Jun 1;24(4):315-7.

    AbstractAll-trans retinoic acid (ATRA), a vitamin A derivative, is prescribed for induction of chemotherapy in patients with acute promyelocytic leukemia. Like other chemotherapy agents, ATRA has an adverse effect known as retinoic acid syndrome. The case of a 22 year old woman with acute promyelocytic leukemia, who received ATRA and subsequently developed retinoic acid syndrome, is presented. The patient's symptoms resolved after administration of dexamethasone, allowing the completion of chemotherapy without further complications.Copyright © 2012 Elsevier Inc. All rights reserved.

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