• Internal medicine · Mar 2021

    Case Reports

    Successfully Treated Case of Cholangiolocellular Carcinoma with a Poor Hepatic Functional Reserve Reporting with Various Imaging Findings.

    • Satoshi Takakusagi, Yozo Yokoyama, Kazuko Kizawa, Kyoko Marubashi, Takashi Kosone, Ken Sato, Satoru Kakizaki, Kenichi Harada, Hitoshi Takagi, and Toshio Uraoka.
    • Department of Gastroenterology and Hepatology, Kusunoki Hospital, Japan.
    • Intern. Med. 2021 Mar 15; 60 (6): 873-881.

    AbstractCholangiolocellular carcinoma (CoCC) is a rare primary liver cancer that is difficult diagnose due to a lack of specific imaging findings. We herein report a case of CoCC accompanied by severe alcoholic cirrhosis. Dynamic computed tomography showed a low-density tumor with a faint surrounding enhancement. Gadolinium-ethoxybenzyl-diethylenetriamine pentaacetic acid-enhanced magnetic resonance imaging revealed iso-intensity in the hepatobiliary phase and a maximum tumor diameter of 53 mm. 18F-fluoro-2-deoxyglucose position-emission tomography was moderately positive (maximum standardized uptake value: 4.3). CoCC was diagnosed based on the pathological findings, including immunohistochemistry. We discuss the diagnostic imaging findings and review previous reports.

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