• Internal medicine · Mar 2021

    Temporal Changes in Brain Perfusion in Neuronal Intranuclear Inclusion Disease.

    • Takuya Ataka, Noriyuki Kimura, and Etsuro Matsubara.
    • Department of Neurology, Oita University, Japan.
    • Intern. Med. 2021 Mar 15; 60 (6): 941-944.

    AbstractWe herein report a patient with neuronal intranuclear inclusion disease (NIID) who presented with encephalitis-like episodes. A neurological examination revealed a disturbance of consciousness without any evidence of encephalitis or epilepsy on laboratory tests. Brain perfusion single-photon emission computed tomography revealed an elevated cerebral blood flow during the encephalitis-like episode and reduced cerebral blood flow in the chronic phase with clinical recovery. This report suggests that the cerebral blood flow of patients with NIID can change over the clinical course. Encephalitis-like episodes of NIID should thus be considered in the differential diagnosis of acute disturbance of consciousness.

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