• Brian Yoshio Laing, Carol M Mangione, Chi-Hong Tseng, Mei Leng, Ekaterina Vaisberg, Megha Mahida, Michelle Bholat, Eve Glazier, Donald E Morisky, and Douglas S Bell.
• Ann. Intern. Med. 2014 Nov 18; 161 (10 Suppl): S5-12.

BackgroundMany smartphone applications (apps) for weight loss are available, but little is known about their effectiveness.ObjectiveTo evaluate the effect of introducing primary care patients to a free smartphone app for weight loss.DesignRandomized, controlled trial. (ClinicalTrials.gov: NCT01650337).Setting2 academic primary care clinics.Patients212 primary care patients with body mass index of 25 kg/m2 or greater.Intervention6 months of usual care without (n = 107) or with (n = 105) assistance in downloading the MyFitnessPal app (MyFitnessPal).MeasurementsWeight loss at 6 months (primary outcome) and changes in systolic blood pressure and behaviors, frequency of app use, and satisfaction (secondary outcomes).ResultsAfter 6 months, weight change was minimal, with no difference between groups (mean between-group difference, -0.30 kg [95% CI, -1.50 to 0.95 kg]; P = 0.63). Change in systolic blood pressure also did not differ between groups (mean between-group difference, -1.7 mm Hg [CI, -7.1 to 3.8 mm Hg]; P = 0.55). Compared with patients in the control group, those in the intervention group increased use of a personal calorie goal (mean between-group difference, 2.0 d/wk [CI, 1.1 to 2.9 d/wk]; P < 0.001), although other self-reported behaviors did not differ between groups. Most users reported high satisfaction with MyFitnessPal, but logins decreased sharply after the first month.LimitationsDespite being blinded to the name of the app, 14 control group participants (13%) used MyFitnessPal. In addition, 32% of intervention group participants and 19% of control group participants were lost to follow-up at 6 months. The app was given to patients by research assistants, not by physicians.ConclusionSmartphone apps for weight loss may be useful for persons who are ready to self-monitor calories, but introducing a smartphone app is unlikely to produce substantial weight change for most patients.Primary Funding SourceRobert Wood Johnson Foundation Clinical Scholars Program, National Institutes of Health/National Center for Advancing Translational Sciences for the UCLA Clinical and Translational Science Institute, and the Resource Centers for Minority Aging Research Center for Health Improvement of Minority Elderly under the National Institutes of Health/National Institute on Aging.

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