• Joint Bone Spine · Oct 2013

    Case Reports

    Antisynthethase syndrome presenting as peripheral limb fasciitis.

    • Mikael Ebbo, Christophe Chagnaud, Dominique Figarella-Branger, Stevan Legall, Jean-Robert Harle, and Nicolas Schleinitz.
    • Service de médecine interne, AP-HM, Aix-Marseille Université, 13385 Marseille cedex 5, France.
    • Joint Bone Spine. 2013 Oct 1; 80 (5): 528-30.

    AbstractInflammatory myopathy is a major clinical manifestation of the antisynthetase syndrome. Patients with anti Jo-1 antibodies can also present with other clinical manifestations as arthritis, mechanic's hands and lung fibrosis. As in dermatomyositis, polymyositis and overlap myopathies proximal muscle of the limbs are preferentialy involved. Associated fascia edema on magnetic resonance imagery studies with histological proven fasciitis has been reported. However peripheral limb involvement, reported here in two patients, as the isolated initial manifestation is unusual. Copyright © 2013 Société française de rhumatologie. Published by Elsevier SAS. All rights reserved.

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