• Mojgan Rahimi, Jalil Makarem, and Pooria Rooyan.
• Department of Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran 1419733141, Iran. drr_anesthesist@yahoo.com
• J Clin Anesth. 2013 Feb 1;25(1):42-6.

Study ObjectiveTo determine the effects of a flash of light in different colors on the frequency and severity of pain during venous cannulation.DesignDouble-blinded, randomized controlled study.SettingOperating room of a university hospital.Patients120 adult, ASA physical status 1 and 2 patients undergoing elective surgery,InterventionsPatients were allocated to 4 groups. Patients' faces were photographed with a camera without first receiving a flash of light (control group), with a flash of white light (white group), a flash of blue light (blue group), or a flash of red light (red group). With a 20-gauge cannula, a vein on the dorsum of the nondominant hand was cannulated immediately after a flash of light.MeasurementsSeverity of pain was measured by Visual Analog Scale (VAS), Verbal Rating Scale (VRS), and FACES Pain Scale (FPS), and frequencies were compared.Main ResultsThe blue group had the lowest pain scores as measured by VAS, followed by the red group, then the white group, all lower than the control group (0.9 ± 0.61, 1.37 ± 0.67, 2.4 ± 1.13, and 4.63 ± 1.5, respectively; P < 0.01). The same pattern emerged regarding frequency of pain (13.3%, 40%, 80% and 100%, respectively; P < 0.01). As for severity of pain measured by VRS and FPS, all intergroup comparisons were significant except for the red and blue groups.ConclusionsApplication of a blue light flash before venous cannulation decreased the frequency and severity of pain associated with venipuncture. This method is an effective, easy to perform, and inexpensive way to reduce pain during venous cannulation.Copyright © 2013 Elsevier Inc. All rights reserved.

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