• J. Clin. Pathol. · Feb 2007

    Children's vaccines do not induce cross reactivity against SARS-CoV.

    • Yang Yu, Huali Jin, Ze Chen, Qingling L Yu, Yijie J Ma, Xiaolin L Sun, and Bin Wang.
    • State Key Laboratory for Agro-Biotechnology, College of Biological Science, China Agricultural University, Beijing, China.
    • J. Clin. Pathol. 2007 Feb 1; 60 (2): 208-11.

    AbstractIn contrast with adults, children infected by severe acute respiratory syndrome-corona virus (SARS-CoV) develop milder clinical symptoms. Because of this, it is speculated that children vaccinated with various childhood vaccines might develop cross immunity against SARS-CoV. Antisera and T cells from mice immunised with various vaccines were used to determine whether they developed cross reactivity against SARS-CoV. The results showed no marked cross reactivity against SARS-CoV, which implies that the reduced symptoms among children infected by SARS-CoV may be caused by other factors.

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