• Liuyang He, Jianzhou Zheng, Lei Xia, Chunjian Qi, Yong Wang, and Mingxia Yang.
• Institute of Heart, Lung and Blood Vessel Diseases, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu, China (He LY, Zheng JZ, Xia L, Wang Y, Yang MX); Central Laboratory, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu, China (He LY, Zheng JZ, Xia L, Qi CJ); Department of Respiratory and Critical Care Medicine, Affiliated Changzhou No.2 People's Hospital of Nanjing Medical University, Changzhou 213000, Jiangsu, China (Yang MX). Corresponding author: Yang Mingxia, Email: cougermx@126.com.
• Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2017 Jul 1; 29 (7): 651-655.

ObjectiveAcute lung injury/acute respiratory distress syndrome (ALI/ARDS) is an inflammatory lung injury induced by a variety of factors, and these diseases are associated with high rates of mortality due to the lack of effective treatments. Based on the latest research in ALI/ARDS, it is widely accepted that generalized inflammatory responses play a critical role in initiating and developing process of ALI/ARDS. We make a brief review on the immune-pathogenesis and the signaling pathways of ALI/ARDS from the perspective of inflammation, thereby helping develop novel therapeutic strategy for treatment of patients with ALI/ARDS.

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