• Critical care clinics · Jan 2021

    Review

    Infectious Disease Complications in Patients with Cancer.

    • Susan K Seo, Catherine Liu, and Sanjeet S Dadwal.
    • Infectious Disease Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10065, USA; Department of Medicine, Weill Cornell Medical College, New York, NY, USA. Electronic address: seos@mskcc.org.
    • Crit Care Clin. 2021 Jan 1; 37 (1): 698469-84.

    AbstractCritically ill patients with cancer are vulnerable to infections because of the underlying malignancy, tumor-directed therapy, immunosuppression, breaches in mucosa or skin, malnutrition, and other factors. Neutropenia remains the most important risk factor for infection. Infectious complications occurring in critically ill patients with cancer can affect the bloodstream, lungs, gastrointestinal tract, central nervous system, urinary tract, and the skin. Pneumonias are the leading cause of infection in patients with cancer admitted to the intensive care unit. Consideration of opportunistic pathogens in the differential diagnosis is important in patients with impaired cellular and/or humoral immunity or compromised splenic function.Copyright © 2020 Elsevier Inc. All rights reserved.

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