• Atencion primaria · May 2006

    Multicenter Study

    [Predictive value of metabolic syndrome in pregnancy for the development of diabetes mellitus and factors of short-term vascular risk for mother and child after birth (gestaMET)].

    • Isabel Fernández Fernández, Beatriz Pascual de la Pisa, and Investigadores del Proyecto gestaMET.
    • Medicina de Familia, Unidad de Investigación del Distrito Sanitario Aljarafe, Nodo Al Andalus en la redIAPP, Servicio Andaluz de Salud, Camas, Sevilla, España.
    • Aten Primaria. 2006 May 31; 37 (9): 517-21.

    ObjectivesTo evaluate the presence of diabetes mellitus (DM) or short-term alterations in glucose metabolism, obesity and vascular risk factors after birth in women with pregnancy metabolic syndrome (PMS). To evaluate the incidence of obesity, lipaemia, glucaemia disorder, blood pressure (BP), or lipid figures in the period after birth in children of women with PMS. DESIGN. Cohort study. SETTING. Forty two primary care centres.ParticipantsStudy cohort (SC): women with PMS and their children. Control cohort (CC): women without primary criteria of PMS and their children.Sample SizeSC, 980 women and CC, also 980. Consecutive sampling.MeasurementsMother: basic data, 75 g oral overload, lipid profile, insulinaemia, toxic habits, nutrition survey, and physical activity. Child: weight, height, BP, nutrition survey, glucaemia, insulinaemia, and lipid profile. Father: basic data, BP, glucaemia, lipid profile, insulinaemia, toxic habits, nutrition survey, and physical activity. We will study genes related to insulin resistance in all subjects.Statistical AnalysisComparison of proportions with *2 test; ANOVA to measure means. Evaluation of effect of intra-uteral exposure through logistical regression and COX regression, whilst controlling potentially confusing and interactive variables.DiscussionThis study will contribute to locating the moment when diabetes and vascular risk start and to finding the optimum moment for starting prevention strategies.

      Pubmed     Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…