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- Matthieu Jabaudon, Raiko Blondonnet, and Lorraine B Ware.
- Department of Perioperative Medicine, CHU Clermont-Ferrand.
- Curr Opin Crit Care. 2021 Feb 1; 27 (1): 465446-54.
Purpose Of ReviewThis article provides an overview of protein biomarkers for acute respiratory distress syndrome (ARDS) and their potential use in future clinical trials.Recent FindingsThe protein biomarkers studied as indices of biological processes involved in the pathogenesis of ARDS may have diagnostic and/or prognostic value. Recently, they also proved useful for identifying ARDS phenotypes and assessing heterogeneity of treatment effect in retrospective analyses of completed clinical trials.SummaryThis article summarizes the current research on ARDS biomarkers and provides insights into how they should be integrated as prognostic and predictive enrichment tools in future clinical trials.Copyright © 2020 Wolters Kluwer Health, Inc. All rights reserved.
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