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- Shannon Wang Clark, Chengyuan Wu, David Boorman, Nohra Chalouhi, Mario Zanaty, and Ashwini D Sharan.
- Neurosurgery. 2015 Aug 1;62 Suppl 1:227-8.
IntroductionDual supraorbital and occipital nerve stimulation (SONS and ONS) have shown promising efficacy in treating primary headaches. However, its functional outcome is not well studied. We report functional outcome of combined SONS and ONS for migraine using verified metrics.MethodsConsecutive patients who have both supraorbital and occipital nerve stimulators and also underwent Migraine Disability Assessment (MIDAS) and Beck Depression Index (BDI) both pre- and postoperatively were studied. Outcome variables included net improvement of ranked MIDAS and BDI scores. Predictor variables included patients with 50% improvement of pain, disability status, number of years from diagnosis to implantation, and narcotic use. Multivariate analysis of variance (MANOVA) was performed to assess the correlation between the outcome and predictor variables.ResultsSixteen patients (12 female; age average 51.8 years) were studied. Follow-up ranged from 5 to 80 months (average 44.5 ± 21.4 months). Eight had a positive response (50% improvement in headache) at most recent follow-up. Fifty percent improvement in headache was the only predictor of outcome variables combined (total MIDAS, MIDAS-B, and BDI) (P = .021). Of note, this improvement in functional outcome was only significant during the perioperative period and not throughout the length of follow-up. No other predictive factors were significantly correlated with the functional outcomes. Among the predictor variables, a strong correlation was found for disability status being inversely related to reporting 50% improvement in headache (r = -0.582).ConclusionIn patients who had positive response to SONS and ONS, functional status as reflected by MIDAS and BDI had overall improvement in perioperative period. Unfortunately, this effect waned over the long-term follow-up.
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