• Injury · Jun 2021

    The rationale behind implant coatings to promote osteointegration, bone healing or regeneration.

    • Kai Borcherding, Gerhard Schmidmaier, Gunther O Hofmann, and Britt Wildemann.
    • Department of Adhesive Bonding Technology and Surfaces, Fraunhofer Institute for Manufacturing Technology and Advanced Materials IFAM, Bremen, Germany.
    • Injury. 2021 Jun 1; 52 Suppl 2: S106-S111.

    AbstractImplant loosening, bone healing failure, implant-associated infections, and large bony defects remain challenges in orthopedic surgery. Implant surface modifications and coatings are being developed to promote osteointegration, prevent colonization by bacteria, and release bioactive factors. The following mini-review briefly discusses the clinical problem, explains the four "osteos", presents examples of coatings used for different orthopedic indications, and finally raises awareness of the coating and translational requirements.Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.

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