• V Ezhil Swanly, L Selvam, P Mohan Kumar, J Arokia Renjith, M Arunachalam, and K L Shunmuganathan.
• Computer Science and Engineering, Jeppiaar Engineering College, Rajiv Gandhi Salai, Chennai 119, India.
• Comput Math Methods Med. 2013 Jan 1; 2013: 864854.

AbstractOne third of the world's population is thought to have been infected with mycobacterium tuberculosis (TB) with new infection occurring at a rate of about one per second. TB typically attacks the lungs. Indication of cavities in upper lobes of lungs shows the high infection. Traditionally, it has been detected manually by physicians. But the automatic technique proposed in this paper focuses on accurate detection of disease by computed tomography (CT) using computer-aided detection (CAD) system. The various steps of the detection process include the following: (i) image preprocessing, which is done by techniques such as resizing, masking, and Gaussian smoothening, (ii) image egmentation that is implemented by using mean-shift model and gradient vector flow (GVF) model, (iii) feature extraction that can be achieved by Gradient inverse coefficient of variation and circularity measure, and (iv) classification using Bayesian classifier. Experimental results show that its perfection of detecting cavities is very accurate in low false positive rate (FPR).

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