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Journal of critical care · Apr 2021
LetterInfluence of respiratory and inflammatory parameters preceding intubation on survival of patients with COVID-19 ARDS- A single centre retrospective analysis.
- N Arulkumaran, J Green, A Khan, T Bonnici, A Longobardo, and M Singer.
- Bloomsbury Institute of Intensive Care Medicine, University College London, UK. Electronic address: nisharulkumaran@doctors.org.uk.
- J Crit Care. 2021 Apr 1; 62: 289291289-291.
AbstractIt remains unclear if intubation and ventilation earlier in the disease course confers a survival advantage in acute respiratory distress syndrome. Our objective was to determine whether patients with COVID-19 who died following mechanical ventilation were more advanced in their disease compared to survivors. Forty-seven patients admitted directly to our centre received ventilation, of who 26 (57%) patients died. The rate of fall in SpO2:FiO2 ratio (p = 0.478) and increasing respiratory rate (p = 0.948) prior to IMV were similar between survivors and non-survivors. Our data support a trial of continuous positive airway pressure prior to IMV in patients with moderate-to-severe COVID-19 ARDS.Copyright © 2021 Elsevier Inc. All rights reserved.
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