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- Takatoshi Enomoto, Takayuki Takimoto, Tomoko Kagawa, Kazunobu Tachibana, Chikatoshi Sugimoto, Toru Arai, Teiko Sakurai, Takahiko Kasai, Masanori Akira, Seiji Hayashi, and Yoshikazu Inoue.
- Department of Internal Medicine, National Hospital Organization Kinki-Chuo Chest Medical Center, Japan.
- Intern. Med. 2021 Jul 15; 60 (14): 2261-2268.
AbstractDendriform pulmonary ossification (DPO) is a rare condition characterized by metaplastic bone formation in the lung parenchyma. It has been reported to be often associated with primary lung diseases, such as usual interstitial pneumonia (UIP) or chronic aspiration of gastric acid; however, its clinical features and pathophysiology remain unclear, especially in idiopathic cases. We herein report five DPO cases, including three with an idiopathic origin. In all cases of idiopathic DPO, the pathological and radiological examinations showed localized pulmonary lesions suggesting inflammation or hemorrhaging.
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