• Internal medicine · Jul 2021

    Case Reports

    Symptomatic Long QT syndrome Coexisting with Asymptomatic Acetylcholine-induced Vasospasm.

    • Toranosuke Sekine, Masashi Kamioka, Naoko Hijioka, Shinya Yamada, Takashi Kaneshiro, and Yasuchika Takeishi.
    • Department of Cardiovascular Medicine, Fukushima Medical University, Japan.
    • Intern. Med. 2021 Jul 1; 60 (13): 2085-2088.

    AbstractWe herein report a rare case of long QT syndrome (LQTS) coexisting with acetylcholine (Ach)-induced vasospasm. A 31-year-old woman experienced cardiopulmonary arrest during running. LQTS was diagnosed by an electrocardiogram, and the coexistence of Ach-induced vasospam was determined by an Ach provocation test on coronary angiography. Although an implantable cardioverter defibrillator was placed, a beta-blocker was not prescribed for two reasons: first, the patient showed Ach-induced vasospasm alone with no symptoms and no ST change by Ach injection, and second, the use of beta-blockers alone in such patients carries a risk of vasospasm-induced ventricular fibrillation.

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