• Medicina clinica · Aug 2021

    Case Reports Multicenter Study Observational Study

    SARS-CoV-2 infection: A predisposing factor for acute coronary syndrome.

    • Cristina de Cortina Camarero, Eloy Gómez Mariscal, Victoria Espejo Bares, Alberto Núñez Garcia, Roberto Muñoz Aguilera, and Javier Botas Rodriguez.
    • Servicio de Cardiología, Hospital Universitario Infanta Leonor, Madrid, España. Electronic address: ccortinac@gmail.com.
    • Med Clin (Barc). 2021 Aug 13; 157 (3): 114-117.

    IntroductionSeveral case series of ACS have been reported in COVID 19 patients. We aim to study its incidence, characteristics, and three-month prognosis. To put this incidence in perspective we compared it with the incidence of in-hospital ACS during the same period of 2019.MethodsObservational multicenter cohort study of 3,108 COVID-19 patients admitted to two hospitals in Madrid between March 1st and May 15th, 2020. Ten patients suffered an ACS while being hospitalized for COVID 19 and were followed for three months. The ACS incidence in hospitalized patients during the same period of 2019 was also studied.ResultsThe incidence of ACS in COVID-19 patients was 3.31 ‰, significantly higher than in the 2019 period, 1.01 ‰ (p = 0.013). COVID-19 patients that suffered and ACS frequently had a severe infection, presented with STEMI (80%), and had multivessel disease (67%). Mortality rate (30%) and hospital readmissions at three months (20%) were very high.ConclusionsSevere COVID-19 patients develop ACS more frequently than expected. Although the overall incidence was low, it carried a poor immediate and three-month prognosis.Copyright © 2021 Elsevier España, S.L.U. All rights reserved.

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