• J Cardiothorac Surg · Jan 2007

    Case Reports

    Acute leukaemoid reaction following cardiac surgery.

    • Nigel E Drury, Ayyaz Ali, Shafi Mussa, Stephen T Webb, Kanchan P Rege, and John Wallwork.
    • Department of Cardiac Surgery, Papworth Hospital, Cambridge, CB23 3RE, UK. nigeldrury@gmail.com
    • J Cardiothorac Surg. 2007 Jan 9; 2: 3.

    AbstractChronic myelomonocytic leukaemia is an atypical myeloproliferative disorder with a natural history of progression to acute myeloid leukaemia, a complex and poorly understood response by the bone marrow to stress. Cardiac surgery activates many inflammatory cascades and may precipitate a systemic inflammatory response syndrome. We present a case of undiagnosed chronic myelomonocytic leukaemia who developed rapidly fatal multi-organ dysfunction following cardiac surgery due to an acute leukaemoid reaction.

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