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- Yukiko Maeda, Kunio Toda, Sono Toi, Tetsundo Yano, Mutsumi Iijima, Yuko Shimizu, Yoji Nagashima, Yasutomo Itakura, Shigekazu Iguchi, Ken Kikuchi, Kazutoshi Shibuya, Manabu Nonaka, and Kazuo Kitagawa.
- Department of Neurology, Tokyo Women's Medical University, Japan.
- Intern. Med. 2021 Aug 15; 60 (16): 2683-2686.
AbstractWe herein report a 73-year-old man who experienced cerebral infarction caused by infection with a Mucromycocetes species. A delay in anti-fungal treatment might result in a lethal clinical outcome. We were unable to establish an accurate diagnosis based on histological findings and cerebrospinal fluid culture. Therefore, we performed polymerase chain reaction (PCR) using paraffin-embedded specimens, and based on the findings, successfully started administering anti-fungal treatment. We suggest that PCR using sinus specimens be applied when mucormycosis is suspected as an etiology of cerebral infarction and a confirmative diagnosis cannot be established based on the results of pathological examinations or cerebrospinal fluid culture.
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