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- Kyoko Gocho, Tokuhiro Kimura, Shinya Matsushita, Saeko Shinozawa, Nobuyuki Hamanaka, Yoshimasa Inoue, and Tamiko Takemura.
- Department of Respiratory Medicine, Saiseikai Yokohamashi Tobu Hospital, Japan.
- Intern. Med. 2021 Oct 1; 60 (19): 3137-3142.
AbstractGood's syndrome is associated with thymoma and acquired immunodeficiency. A 54-year-old man visited our hospital with a complaint of cough. Chest imaging revealed diffuse nodular shadows and anterior mediastinal mass. Hypogammaglobulinemia and a decreased B lymphocyte count were found by a laboratory evaluation. The lung nodules markedly regressed after immunoglobulin therapy. The mediastinal mass and remaining nodule were surgically resected and diagnosed as a type AB thymoma and a necrotizing epithelioid granuloma with T lymphocyte-dominant alveolitis, respectively. The overall appearances of these lesions were mostly in line with the spectrum of granulomatous-lymphocytic interstitial lung disease associated with Good's syndrome.
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