• Respiratory investigation · Sep 2020

    Single-center experience of patients with interstitial lung diseases during the early days of the COVID-19 pandemic.

    • J Guiot, M Henket, A N Frix, M Delvaux, A Denis, L Giltay, M Thys, F Gester, M Moutschen, J L Corhay, R Louis, and COVID-19 clinical investigators of the CHU de Liège.
    • Pneumology Department, CHU Liège, Domaine Universitaire Du Sart-Tilman, B35, B4000 Liège, Belgium. Electronic address: J.Guiot@chuliege.be.
    • Respir Investig. 2020 Sep 19.

    IntroductionPatients with interstitial lung diseases (ILD) can be suspected to be at risk of experiencing a rapid flare-up due to COVID-19. However, no specific data are currently available for these patients.MethodsWe retrospectively analyzed a cohort of 401 patients with ILD and determined the proportion of patients hospitalized for proven severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and specific symptoms of COVID-19.ResultsWe found that 1% of patients (n = 4) were hospitalized (1 in ICU) for COVID-19. In total, 310 of the 401 patients answered the phone call. Only 33 patients (0.08%) experienced specific symptoms of SARS-CoV-2 infection.ConclusionOur study did not demonstrate any increased occurrence of severe COVID-19 in ILD patients compared to the global population. Based on our findings, we could not make any conclusion on the incidence rate of SARS-CoV-2 infection in patients with ILDs, or on the overall outcome of immunocompromised patients affected by COVID-19.Copyright © 2020 The Japanese Respiratory Society. Published by Elsevier B.V. All rights reserved.

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