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Afr J Paediatr Surg · Jul 2015
Case ReportsVisceral basidiobolomycosis: An overlooked infection in immunocompetent children.
- Parkash Mandhan, Kamal Osman Hassan, Sandra Moustafa Samaan, and Mansour J Ali.
- Department of Pediatric Surgery, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar.
- Afr J Paediatr Surg. 2015 Jul 1; 12 (3): 193-6.
AbstractVisceral basidiobolomycosis is an unusual fungal infection of viscera caused by saprophyte Basidiobolus ranarum. It is very rare in healthy children and poses a diagnostic challenge due to the non-specific clinical presentation and the absence of predisposing factors. We report a case of gastrointestinal basidiobolomycosis in a 4-year-old healthy girl who presented with a short history of abdominal pain, bleeding per rectum, fever, and weight loss. The diagnosis was based on high eosinophilic count, classical histopathology findings of fungal hyphae (the Splendore-Hoeppli phenomenon), and positive fungal culture from a tissue biopsy. Fungal infection was successfully eradicated with a combined approach of surgical resection of the infected tissue and a well-monitored course of antifungal therapy. The atypical clinical presentation, diagnostic techniques, and the role of surgery in the management of a rare and lethal fungal disease in an immunocompetent child are discussed.
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