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Zhongguo Zhong Yao Za Zhi · Apr 2001
Comparative Study[Preliminary studies on process and ultramicro-pulverization on pharmacodynamics of Leech].
- W H Lu, F J Qiu, and Z M Wang.
- Shandong University of Trditional Chinese Medicine, Jinan 250014, Shandong, China.
- Zhongguo Zhong Yao Za Zhi. 2001 Apr 1; 26 (4): 241-4.
ObjectiveTo compare pharmacodynamics of decoction and powder of Leech; To identify effect of pharmacodynamics of Leech with new methods of process and ultrmicro-pulverization.MethodThe size of ultramicor-powder of Leech and new method processed Leech is determined by BT-1500 size distributive instrument. It is compared that the pharmacodynamics of Leech decoction and powder as well as ultramicro-powder with new method processed of 1/2 decoction dose by anticoagulation and antithrombus action of mice. The safety of different samples is identified.ResultThe pharmacodynamics of samples is as ultramicro-powder of Leech with new method processed > ultrmicro-powder of Leech > powder of Leech > decoction of Leech.ConclusionThe ultramicro-powder of Leech with new method processed has better pharmacodynamic effect and the smell of Leech is improved.
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