• Clin. Exp. Allergy · May 1989

    Comparative Study

    Allergic reactions to the Australian paralysis tick, Ixodes holocyclus: diagnostic evaluation by skin test and radioimmunoassay.

    • M Gauci, R K Loh, B F Stone, and Y H Thong.
    • CSIRO, Division of Tropical Animal Production, Long Pocket Laboratories, Indooroopilly, Queensland, Australia.
    • Clin. Exp. Allergy. 1989 May 1; 19 (3): 279-83.

    AbstractAllergic reactions to Ixodes holocyclus are well recognized but poorly defined. Tick-bite reactions in 42 individuals in this study fell into six classes. Skin-prick tests and radioimmunoassay (RIA) indicated that all systemic hypersensitivity (class 3) and atypical reactions (class 4) were IgE-mediated. Some 73% of the large local reactions (class 2) and only 12.5% of the small local reactions (class 1) were associated with IgE specific for tick allergens. Subjects who reported heavy exposure to tick-bite were more likely to have positive RIA values (P less than 0.05). There was an association between the individual's atopic status and tick allergy (P greater than 0.05).

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