• Eur Spine J · Feb 2014

    Meta Analysis Comparative Study

    Comparison of unilateral versus bilateral pedicle screw fixation in lumbar interbody fusion: a meta-analysis.

    • Wenbin Ding, Yile Chen, Hui Liu, Jianru Wang, and Zhaomin Zheng.
    • Department of Spine Surgery, First Affiliated Hospital of Sun Yat-sen University, No. 58 Zhongshan Er Road, Guangzhou, 510080, People's Republic of China.
    • Eur Spine J. 2014 Feb 1; 23 (2): 395-403.

    PurposeThis is a meta-analysis to compare the clinical results between unilateral and bilateral pedicle screw (PS) fixation in lumbar interbody fusion.MethodsWe included published studies with no language and year restrictions. The criteria which Koes et al. designed in 1995 were used to evaluate the risk of bias of the included studies. All data were analyzed by Review Manager 5.1. The primary outcomes included fusion rate and screw complications, and the secondary outcomes were operative time, blood loss, and hospital time.ResultsA total of five prospective studies with 407 patients were included in the current meta-analysis, and four of them were randomized controlled trials. There was no significant difference between unilateral PS fixation and bilateral PS fixation group in fusion rate and screw complications (fusion rate: OR 0.54, Z = 1.33, P = 0.18, I (2) = 0 %; screw complications: OR 1.45, Z = 0.71, P = 0.48; I (2) = 44 %). In the secondary outcomes, the operative time (Z = 3.35, P = 0.0008; I (2) = 95 %) and blood loss (Z = 4.35, P < 0.0001; I (2) = 98 %) was significantly higher in bilateral PS fixation group than in unilateral PS fixation group. Besides, no significant difference was found in hospital time (Z = 1.19, P = 0.24; I (2) = 99 %).ConclusionsIn our meta-analysis, we found that unilateral PS fixation in lumbar fusion was as effective as bilateral PS fixation for lumbar degenerative diseases without major instability, no significant difference was found in hospital time, fusion rate and screw complications. In terms of operative time and blood loss, unilateral PS fixation even produced better results.

      Pubmed     Full text   Copy Citation     Plaintext  

      Add institutional full text...

    Notes

     
    Knowledge, pearl, summary or comment to share?
    300 characters remaining
    help        
    You can also include formatting, links, images and footnotes in your notes
    • Simple formatting can be added to notes, such as *italics*, _underline_ or **bold**.
    • Superscript can be denoted by <sup>text</sup> and subscript <sub>text</sub>.
    • Numbered or bulleted lists can be created using either numbered lines 1. 2. 3., hyphens - or asterisks *.
    • Links can be included with: [my link to pubmed](http://pubmed.com)
    • Images can be included with: ![alt text](https://bestmedicaljournal.com/study_graph.jpg "Image Title Text")
    • For footnotes use [^1](This is a footnote.) inline.
    • Or use an inline reference [^1] to refer to a longer footnote elseweher in the document [^1]: This is a long footnote..

    hide…

What will the 'Medical Journal of You' look like?

Start your free 21 day trial now.

We guarantee your privacy. Your email address will not be shared.