• Biosens Bioelectron · Mar 2021

    Review

    The potential application of electrochemical biosensors in the COVID-19 pandemic: A perspective on the rapid diagnostics of SARS-CoV-2.

    • Sahar Sadat Mahshid, Sarah Elizabeth Flynn, and Sara Mahshid.
    • Biological Sciences Department, Sunnybrook Research Institute, Toronto, ON, M4N 3M5, Canada. Electronic address: sahar.mahshid@sri.utoronto.ca.
    • Biosens Bioelectron. 2021 Mar 15; 176: 112905.

    AbstractElectrochemical biosensors combine the selectivity of electrochemical signal transducers with the specificity of biomolecular recognition strategies. Although they have been broadly studied in different areas of diagnostics, they are not yet fully commercialized. During the COVID-19 pandemic, electrochemical platforms have shown the potential to address significant limitations of conventional diagnostic platforms, including accuracy, affordability, and portability. The advantages of electrochemical platforms make them a strong candidate for rapid point-of-care detection of SARS-CoV-2 infection by targeting not only viral RNA but antigens and antibodies. Herein, we reviewed advancements in electrochemical biosensing platforms towards the detection of SARS-CoV-2 through studying similar viruses.Copyright © 2020 Elsevier B.V. All rights reserved.

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