• Br. J. Haematol. · Mar 2021

    Paradoxical effect of SARS-CoV-2 infection in patients with immune thrombocytopenia.

    • Beatriz de la Cruz-Benito, María I Rivas-Pollmar, María T Álvarez Román, Roberto Trelles-Martínez, Monica Martín-Salces, Paula Lázaro-Del Campo, Andrés Ramírez-López, Sara García-Barcenilla, Tamara Cebanu, Paula Acuña-Butta, Elena Monzón-Manzano, Elena González-Zorrilla, Victor Jiménez-Yuste, and Nora V Butta.
    • Unit of Thrombosis and Hemostasis, Hematology Department, La Paz University Hospital - IdiPAZ, Madrid, Spain.
    • Br. J. Haematol. 2021 Mar 1; 192 (6): 973-977.

    AbstractThrombocytopenia has been identified as a common complication of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection in the general population. In an attempt to determine the impact of coronavirus disease 2019 (COVID-19) in patients with immune thrombocytopenia (ITP), a retrospective single-centre study was performed. Thrombocytosis was observed in patients with chronic ITP after SARS-CoV-2 infection, frequently needing treatment adjustment or even discontinuation of therapy. Relapses and newly diagnosed cases showed a fast response after initial treatment compared to ITP. Reduced immune activity due to lymphopenia during COVID-19 could explain this paradoxical effect, although further studies are needed.© 2020 British Society for Haematology and John Wiley & Sons Ltd.

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