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- Shusuke Yagi, Tomoko Takahashi, Keiji Murakami, Momoyo Azuma, Mikio Sugano, Ryosuke Miyamoto, Mariko Niki, Hirotsugu Yamada, Yutaka Kawabata, Akihiro Tani, Daiju Fukuda, Muneyuki Kadota, Takayuki Ise, Kenya Kusunose, Takeshi Tobiume, Tomomi Matsuura, Koji Yamaguchi, Takeshi Soeki, Tetsuzo Wakatsuki, Hiroki Hata, and Masataka Sata.
- Department of Cardiovascular Medicine, Tokushima University Graduate School of Biomedical Sciences, Japan.
- Intern. Med. 2021 Oct 15; 60 (20): 3251-3255.
AbstractInfective endocarditis (IE) may be acquired in the community as community-acquired (CA) IE or in the healthcare setting. In Japan, cases of CA-methicillin-resistant Staphylococcus aureus (MRSA) infection as skin infection have been increasing. CA-MRSA strains, including the USA300 clone, have higher pathogenicity and are more destructive to tissue than healthcare-associated MRSA strains because of the toxins they produce, including arginine-catabolic mobile element (ACME) and Panton-Valentine leukocidin (PVL). However, only a few IE cases induced by USA300 have been reported. We herein report a 64-year-old man who developed CA-IE from a furuncle caused by USA300 MRSA producing PVL and ACME, which resulted in complications of meningitis.
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