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  • J. Med. Microbiol. · Dec 2012

    Case Reports

    Gastrointestinal basidiobolomycosis, an emerging infection in the immunocompetent host: a report of 14 patients.

    • Bita Geramizadeh, Razieh Foroughi, Marzieh Keshtkar-Jahromi, Seyed-Ali Malek-Hosseini, and Abdolvahab Alborzi.
    • Department of Pathology, Shiraz University of Medical Sciences, PO Box 71345-1864, Shiraz, Iran.
    • J. Med. Microbiol. 2012 Dec 1; 61 (Pt 12): 1770-1774.

    AbstractZygomycosis is characterized by tissue invasion with broad, non-septate hyphae of species such as Rhizopus, Rhizomucor, Lichtheimia (Absidia) and Basidiobolus. Basidiobolus ranarum usually causes subcutaneous infection, and gastrointestinal manifestations in immunocompetent patients have rarely been reported. It is difficult to diagnose gastrointestinal basidiobolomycosis because of the non-specific clinical presentation and the absence of a definite risk factor. This study identified 14 cases of gastrointestinal basidiobolomycosis, all of which were diagnosed after surgery by characteristic histopathological findings. Diagnosis of this disease requires a high index of suspicion in patients presenting with abdominal symptoms, fever, gastrointestinal mass and eosinophilia accompanied by a high erythrocyte sedimentation rate.

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