• Internal medicine · Oct 2021

    Case Reports

    A Case of Gastric Cancer with Multiple Lymph Node Enlargement at the Time of the Sarcoidosis Diagnosis.

    • Yasuyuki Tanaka, Yumi Tokubayashi, Mitsuya Kikuchi, Shigehiko Fujii, Toshihiro Kusaka, Shinsuke Shibuya, and Hiroyuki Kokuryu.
    • Department of Gastroenterology and Hepatology, Kyoto Katsura Hospital, Japan.
    • Intern. Med. 2021 Oct 15; 60 (20): 3225-3229.

    AbstractAn 80-year-old woman was found to have a 40-mm depressed-type gastric cancer. Computed tomography showed multiple lymph node enlargement, including paraaortic lymph nodes. The extent of lymph node enlargement was significant compared with the depth of the primary lesion. We conducted distal gastrectomy, D2 lymph node dissection, and a paraaortic lymph node biopsy. Microscopically, the tumor was diagnosed as mucosal cancer. In the dissected lymph nodes, noncaseating granuloma was found without metastasis of adenocarcinoma. Immunohistochemical staining using Propionibacterium acnes-specific antibodies showed a large number of P. acnes-positive cells in the granulomas. Finally, the tumor was diagnosed as early-stage gastric cancer and sarcoidosis.

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