• Nat. Struct. Mol. Biol. · Nov 2007

    Cross-regulation of histone modifications.

    • John A Latham and Sharon Y R Dent.
    • Program in Genes and Development, Department of Biochemistry and Molecular Biology and Center for Epigenetics, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA.
    • Nat. Struct. Mol. Biol. 2007 Nov 1; 14 (11): 1017-24.

    AbstractHistones undergo several different post-translational modifications that control a variety of physiological processes. These covalent modifications show substantial cross-regulation, providing a wealth of regulatory potential. New insights into the communication between modifications on histones have emerged in recent years. This review assesses the current understanding of cross-regulation of histone modifications and identifies future questions to be addressed in this field.

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