• Immunity · Feb 2021

    Review

    B cell memory: understanding COVID-19.

    • Isaak Quast and David Tarlinton.
    • Department of Immunology and Pathology, Monash University, 89 Commercial Road, Melbourne, VIC 3004, Australia.
    • Immunity. 2021 Feb 9; 54 (2): 205-210.

    AbstractImmunological memory is a mechanism to protect us against reinfection. Antibodies produced by B cells are integral to this defense strategy and underlie virtually all vaccine success. Here, we explain how B cells memory is generated by infection and vaccination, what influences its efficacy and its persistence, and how characterizing these parameters in the immune response to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) will help achieve protective immunity through vaccination.Crown Copyright © 2021. Published by Elsevier Inc. All rights reserved.

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