• Helv Paediatr Acta · Aug 1976

    Case Reports

    Zinc therapy in acrodermatitis enteropathica.

    • D Leupold, J R Poley, and W N Meigel.
    • Helv Paediatr Acta. 1976 Aug 1; 31 (2): 109-15.

    AbstractAn infant is described with acrodermatitis enteropathica, who initially presented with severe and intractable watery diarrhea. Diagnosis was established at the age of eleven weeks. Serum-zinc concentrations were extremely low and urinary zinc excretion was diminished. Eleven days after oral zinc supplement (100 mg elemental zinc per day), the skin lesions had healed. The high therapeutic doses of zinc required for healing are suggestive that zinc malabsorption is an important pathogenetical factor of this disease.

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