• J. Int. Med. Res. · Dec 2018

    Randomized Controlled Trial

    Analgesic effect of preoperative dezocine-based local anesthesia in patients undergoing inguinal hernia repair.

    • Xingwen Liu, Jing Hu, Liqun Gao, Xuewen Ji, Duxiu Zhai, Huixia Song, Xueying Wu, and Liying Wang.
    • Department of Liver Transplantation and Laparoscopic Surgery, Digestive and Vascular Surgery Centre, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830011, China.
    • J. Int. Med. Res. 2018 Dec 1; 46 (12): 4945-4951.

    ObjectiveThis study was performed to investigate the analgesic effects of intramuscular injection of dezocine-based local anesthesia in patients undergoing inguinal hernia repair.MethodsA total of 120 patients underwent local herniorrhaphy from July 2015 to December 2016 and were randomly divided into 2 groups: the dezocine group, in which a preoperative intramuscular injection of dezocine was administered, and the control group, in which no dezocine injection was administered. The patients' pain and comfort levels were evaluated at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours postoperatively.ResultsThe visual analog scale scores at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours were significantly lower in the dezocine than control group. In the Bruggemann comfort scale evaluation, patients who received dezocine injections showed significantly greater comfort than those in the control group at 30 minutes, 2 hours, 6 hours, 12 hours, and 24 hours. No adverse reactions occurred in the dezocine group.ConclusionsDezocine-based local anesthesia can attenuate postoperative pain and increase the comfort level during and after herniorrhaphy.

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